There are some general rules which you can apply when using the comma. However, you will find that in English there are many other ways to use the comma to. The comma has several uses in English grammar, all related to marking-off Rule 1. Use commas to separate words and word groups in a simple series of. The main rule for the use of commas in English is: Keep your sentences clear. Too many commas might be distracting; too few might make the text difficult to. I am, by the way, very nervous about. The following is a short guide to get you started using commas. When the last comma in a series comes before and or or after daughter-in-law in the above exampleit is known as the Oxford comma. Adverbs that don't end in "ly," such as "when" or "while," usually introduce a dependent clause, which rule number two in this post already covered. Use a comma to set off a non-defining subordinate clause or an appositive. If we were to eliminate the second "I" from that example, the second clause would lack a subject, making it not a clause at all.